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On the other hand, boron can increase the intracellular levels of MMP-2 and 9 in keratinocytes in vitro , which is essential for wound healing ( Activated leukocytes release serine proteases, a sub-group of proteolytic enzymes, including elastase, chymase, and cathepsin G that play pivotal roles in the inflammatory response (Hunt and Idso, 1999
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