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Infection of Helicobacter pylori contributes to the progression of gastric cancer through ferroptosis | Cell Death Discovery

In our opinion, the COPD study (Campbell et al.) is the most representative in this aspect, because not only were the gene signatures derived from areas with histologically confirmed pathology, but also GHK’s effects on affected lung tissue were tested in vitro and their correlation to gene effects was well-established [37]

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To better understand differences and similarities in the epigenetics of CSCs and those of the other cancer cells in the bulk tumour, there is a need for more comparisons of their DNA epigenetics (including hydroxymethylomes), chromatin epigenetics, and transcriptomics, preferably by single-cell techniques on in vivo-derived samples