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The central role of glutathione peroxidase 4 in the regulation of ferroptosis and its implications for pro-inflammatory cytokine-mediated beta-cell death - ScienceDirect
Over the past decade, peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α) has been demonstrated as a key transcriptional co-activator, providing a mechanistic insight into nuclear regulatory pathways in the biogenesis of mitochondria in skeletal muscle [7-9]
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Scent:Mysterious Fig
Anti–IL-5 therapies that deplete eosinophils have confirmed their central role in driving exacerbations, although eosinophils are likely downstream effectors of Th2 and ILC2 signaling rather than primary initiators
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